Research Associate, Next Gen Sequencing
Colossal Biosciences · Dallas–Fort Worth, TX
📍 Dallas, TXvia greenhousePosted 2026-06-24
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Colossal is seeking a Research Associate who will take on large-scale genome sequencing initiatives for species conservation and de-extinction in a core lab. They will expand on tools and methodologies to optimize sequencing data flow while maintaining and enhancing workflows to track samples from submission to data delivery.
This position is based on-site in Dallas, TX.
Duties and Responsibilities:
Maintain a thorough and detailed electronic lab notebook
Library preparation and sequencing - ONT platform
UHMW gDNA extraction and preparation for optical genome mapping - Bionano
Perform structure and copy number variant analyses
Utilize and adapt robotic automation for NGS workflows (Firefly Plus)
Maintain a clean and organized laboratory space
Required Skills and Abilities:
Capable of working in a fast-paced, high volume sequencing core on parallel projects, while maintaining accuracy and timely data transfer
Self-motivated, flexible, proactive, works well under pressure and deadlines, detail-oriented
Enthusiastic to learn new skills and take on new responsibilities
Creative problem-solver who can perform technical trouble-shooting
Communicates clearly and proactively to ensure data delivery to stakeholders
Preferred Experience:
Familiarity with UHMW gDNA isolation and optical genome mapping (Bionano)
Comfortable with working in a core lab and communicating with stakeholders.
Experience in library preparation and sequencing using the Oxford Nanopore Technology platform
Education and Experience:
BA/BS with 1+ years of hands-on research in bioengineering, molecular biology, genetics or related fields, such as computational biology
What Colossal Offers Full-Time Employees:
Medical, dental, and vision coverage
Excellent paid time off and company holidays so you can rest and recharge
Flexible spending accounts (FSA)
Company matched 401k retirement plan
Paid parental leave at 100% salary for up to 12 weeks
Education reimbursement
An opportunity to help us return the Earth to a healthier state
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
EEO is the Law
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.
Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:
#1 on the 50 Best Startups to Work For in Dallas in 2023!
100 Best Midsize Places to Work in Dallas in 2024 & 2025
100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.
Built In 2026 Award Lists
Great Place to Work Certification Page
Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.
Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!
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