Senior Project Manager
Definium Therapeutics, Inc. · Remote
📍 Remote💰 $130,000via greenhousePosted 2026-06-01
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Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.
Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.
Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.
Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!
The ideal candidate enjoys working in a rapidly growing environment with strong focus on execution, navigating multiple stakeholders and priorities, and has an excellent understanding of formal project management methodologies, preferably including experience in using Planisware Enterprise. The Sr. Project Manager will lead the development of Project plan(s) to support functional areas or workstreams. Closely and proactively monitor the execution of the project plans and deliverables to ensure successful delivery of the program milestones, company milestones, and objectives. Anticipate potential risks and problems (e.g. resource bottlenecks, risks to critical milestones, inefficient processes) and proactively develop risk mitigation plan.
Responsibilities:
Excellent communication and interpersonal skills. Networking and stakeholder management skills
Experience working in a highly matrixed organization with geographically dispersed teams
Problem solving and decision-making skills. Demonstrated ability to drive initiatives, solve issues (conflict management and facilitation skills), anticipate problems and achieve objectives, while keeping an eye on the big picture
Strategic and analytical thinking skills to assimilate complex information, operate effectively in situations of ambiguity and simplify complex issues
Understanding/experience working within a functional area such as clinical, preclinical, CMC or regulatory affairs would be considered beneficial
Full understanding of drug development business processes
High competence in use of Microsoft Office, Microsoft Project or equivalent and other PM appropriate tools
Experience with Planisware Enterprise and Office Timeline is preferred but not required
Requirements:
Bachelor’s Degree with 8+ years’ experience in the Pharmaceutical / Biotech industry
Minimum 5+ years' experience in project/program management roles in the pharma/biotech industry
Experience in late phase development organizations
Experience with NDA submissions is preferable
Familiarity of working with clinical trials from a project/program management stance
The starting base pay range for this position is $130,000.00 - $160,403.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.
Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:
100% paid health benefits including Medical, Dental and Vision for you and your dependents
401(k) program with company match and vesting after the turn of the first month after your start date
Flexible time off
Generous parental leave and some fun fringe perks!
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