Director, Statistical Programming

The Opportunity Maze is looking for a  Director of Statistical  Progr ammi ng , who will  help  shap e   the  data foundation  of our  clinical development  programs . In thi s role   y ou’ll  collaborate  closely with  colleagues across  Biostatistics, Clinical Data Management, Clinical Operations, and Regulatory Affairs, and oversee external vendors to  keep   our  studies  rigorous, high-quality, and ready for regulatory review .   You’ll  report to the Vice President of Biometrics and lead   the stra tegy and day-to-day execution  of  statistical programmi ng  across multiple clinical  studies .  You r leadership will ensure  we deliver  reliable, efficient , and regulatory-c ompliant  programming   outputs  that drive smarter decisions and ad vance our therapeutic programs.   The Impact You’ll Have Define and implement statistical programming  strategy , standards, and best practices across development programs .   Lead  the design, development, validation , and maintenance of SAS macros, scripts, and applications supporting clinical data analysis, reporting, and regulatory deliverables (e.g., SDTM,  ADaM  datasets, TLFs) .   Ensure programming infrastructure is robust , scalable, and compliant with regulatory standards (e.g., FDA 21 CFR Part 11,  GxP ), and supports reproducibility and audit readiness .   Drive  automation and standardization of programming  workflows to improve efficiency and consistency across studies .   Partner closely  with Biostatistics, Clinical Data Management, Regulatory Affairs , and IT to define programming requirements,  align on  analysis/reporting deliverables, and ensure data integrity .   Represent the statistical programming function  in cross-functional meetings and strategic initiatives .   Manage CROs and external programming vendors , including scope, timelines, quality, and budget oversight .   Support outsourcing strategy  and vendor selection As a Director , we also expect you to demonstrate the following Leadership Competencies: Communication and Influence Builds communication channels across Maze for sharing information. Influences Senior Management decisions through persuasive arguments. Respectfully addresses differing opinions leading to support of decisions. Teamwork and Collaboration Champions partnerships and connections across Maze. Proactively addresses issues that could result in breakdown of team relationships. Spotlights team and individual contributions in public forums. Execution and Results Addresses gaps and leverages strengths to get best results. Maintains a steadying presence and clarifies priorities during change. Anticipates and removes barriers that put functional/corporate goals at risk. Develop Others and Self Remove barriers to staff development and empowers them to make their own decisions. Stays current on industry trends and keeps direct-reports prepared and responsive. What We’re Looking For An  advanced degree in Statistics, Computer Science, Mathematics, or related discipline   Master’s degree with 10+ years of experience, or Ph.D. with 8+ years of  experience   A track record of leading statistical programming efforts across multiple clinical studies or regulatory submissions.    Strong decision-making skills and the  a bility to  guide teams through ambiguity   while influencing across  project teams.     A collaborative leadership  style   that emphasizes mentorship, knowledge   sharing, and developing others.   Deep technical  expertise  in statistical programming for clinical research, with familiarity in CDISC standards, submission ‑ ready deliverables, and modern programming best practices.   This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week.     About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.  Our Core Values Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.  Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True – Our integrity is foundational; it guides us no matter the obstacle. The expected annual salary range for employees located in the San Francisco Bay Area is $229, 000 - $279,000 . Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future. Maze offers a robus