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Senior Director, Talent Acquisition & HRBP

Maze Therapeutics, Inc. · San Francisco Bay Area

📍 South San Francisco, CA💰 $270,000 - $330,000via greenhousePosted 2026-05-29
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The Position We are seeking a Senior Director, Talent Acquisition & HRBP to lead hiring strategy and execution as the company advances its lead program into late ‑ stage development and prepares for continued organizational growth. This role is critical to ensure we attract, assess, and hire the talent required to deliver on our clinical and corporate priorities, while also serving as a strategic people partner to the business.   The Senior Director will work closely with executive leadership, functional leaders, and the broader People team to build scalable, high ‑ quality hiring capabilities. Depending on the experience, interest, and capabilities of the individual hired, this role will also include Human Resources Business Partner (HRBP) responsibilities for select functions.   The Impact You’ll Have Talent Acquisition Strategy   Own and execute a company ‑ wide talent acquisition strategy aligned with late ‑ stage development milestones and growth plans.   Lead, coach, and develop the Talent Acquisition team, including recruiters, coordinators, and other recruiting resources as the organization scales.   Translate business priorities and program timelines into hiring plans and recruiting strategies.   Build proactive pipelines across core biotech talent markets and manage search firms, contractors, and recruiting vendors.   Advise leaders on hiring sequencing, role scoping, and talent tradeoffs as the organization scales.   Hiring Execution & Process Excellence   Partner with functional leaders to recruit for critical clinical, scientific, technical, and operational roles.   Ensure hiring processes are efficient, rigorous, inclusive, and appropriate for a late ‑ stage biotech environment.   Oversee and manage relationships with external search partners.   Continuously refine Talent Acquisition strategy and practices to ensure a strong candidate experience and high ‑ quality outcomes.   Workforce Planning & Organizational Scaling   Collaborate with leadership and translate company milestones, portfolio priorities, and organizational plans into hiring roadmaps, tied to organizational needs.   Provide input into org design discussions related to growth, team structure, and build ‑ vs ‑ buy decisions.   Use market data and benchmarks to inform hiring and resourcing decisions.   HR Business Partner Responsibilities   Serve as an HR Business Partner to designated functions, providing strategic people guidance and support.   Partner with leaders on organizational design, role clarity, team effectiveness, performance management and change management.   Act as a trusted advisor to leaders navigating growth, complexity, and evolving organizational needs.   As a  Senior Director , we also expect  you  to  demonstrate  the following Leadership Competencies:    Leadership Competencies Communication and Influence Role models clear communication and open two-way conversations.   Reinforces an environment where people feel heard and their opinions are valued.   Inspires followership despite differing initial opinions.   Teamwork and Collaboration Champions collaborations and connections across Maze.   Establishes team norms and expectations.   Seeks opportunities to spotlight team and individual contributions in public forums.   Execution and Results Develops recommendations to  seize on  opportunities and mitigate obstacles that could  impact  long-term success.   Coaches  others on resource management and work distribution/delegation.   Aligns work to Maze’s strategy, mission, and vision.   Develop Others and Self Develops staff capabilities to handle delegation of responsibilities.   Encourages staff to develop and execute personal stretch goals.   Identifies and recommends ways to increase inclusive leadership.   What We’re Looking For Degree and experience  12+ years of progressive experience in Talent Acquisition and HR leadership roles ideally within biotechnology, life sciences, or other high ‑ growth environments. (Prefer demonstrated success in building and scaling talent acquisition function in late-stage clinical organization)   5+ years of people management experience leading teams in a biotech, biopharma, or similarly complex growth-stage environment   Experience hiring across clinical development, technical operations, scientific, regulatory, quality, and corporate functions   Strong judgement as it relates to hiring prioritization, and organizational tradeoffs decisions   Ability to influence senior leaders and operate effectively in a dynamic environment   Experience serving as an HR Business Partner or comfort operating in a hybrid TA/HRBP role This role follows an onsite schedule, with an expectation to be onsite at our South San Francisco headquarters at least five days per week.     About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While

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