Clinical Laboratory Associate II

About Karius Karius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Position Summary The Clinical Laboratory Associate II (CLA II) is an enthusiastic, self-motivated individual with great communication skills.  Along with the duties described below, this individual performs sample receiving and accessioning, performs routine preventive equipment and instrument maintenance, and assists in the performance of high complexity laboratory testing on patient specimens under the direct supervision of a CLS. The CLA II must demonstrate a high level of individual responsibility and accountability and possess the ability to perform to the requirements listed below. The CLA II must be comfortable in a rapidly evolving Biotech start-up environment.  Shift: Monday to Friday, 7:00 am to 3:30 pm Why Should You Join Us? Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The products Karius offers today are some of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our tests are the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale. Reports to: Sr. Manager, Clinical Laboratory Operations Location: Redwood City, CA Primary Responsibilities Under supervision of licensed personnel, perform high complexity testing for commercial samples in accordance with applicable regulatory requirements and laboratory SOPs. For non-commercial or clinical study samples, perform routine molecular test procedures including specimen processing, nucleic acid extraction, quantitative analysis, PCR, library construction, sequencing, and data analysis. Receive, unbox, and accession inbound biological samples per relevant SOPs; collaborate with the customer support team to obtain information necessary to complete the accessioning process. Prepare samples for processing in accordance with good laboratory practices and established contamination control procedures. Operate high-throughput integrated automation workstations and utilize laboratory information management systems (LIMS) and other infrastructure software in the performance of job duties Perform and document routine preventive maintenance for laboratory equipment and instruments. Support regulatory compliance through adherence to laboratory policies and procedures, and accurately document work performed. Flag SOPs for update; author or revise laboratory SOPs as directed. Identify, escalate, and support process improvement initiatives as appropriate. Provide training and support to junior or new laboratory staff as assigned. Perform all delegated activities as assigned in support of established timelines and quality standards. Perform additional duties as assigned by supervisory or laboratory leadership personnel In addition to those listed above, perform all duties and responsibilities of the CLA I position. What’s Fun About the Job? Karius is operating at the edge of what is now known to be possible in diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. Travel: No travel required. Physical Requirements Hours and days may vary depending on operational needs Standing or sitting for long periods of time may be necessary. May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation  Manual dexterity as repetitive manual pipetting may be necessary Some lifting (up to 25 pounds) may be necessary Position Requirements Bachelor’s degree in Biological science or similar field required.  3+ (three) years of clinical laboratory experience, with 2+ (two) years of pertinent industry experience and increasing levels of responsibility within a molecular biology laboratory. Demonstrated ability to manage projects independently, or with minimal supervision. Prior experience with Next-Generation Sequencing (NGS) preferred. Knowledge of aseptic techniques used in a microbiology laboratory is highly preferred. Personal Qualifications Demonstrates personal accountability of assigned work and processes, consistently delivering results with quality, consistency, and attention to detail. Recognizes, communicates, and escalates issues, risks, or deviations in a timely and transparent manner.    Adapts effectively to changing priorities and operational demands in a dynamic laboratory environment. Demonstrates awareness of how individual responsibilities impact adjacent workflows and overall laboratory operations. Demonstrates curiosity and learning agility, seeking to understand broader laboratory processes beyond immediate tasks and remaining open to feedback, coaching, and continuous skill development. Maintains a collaborative, respectful,