Director, Patient Centered Science, Late CVRM

The  Patient   Centered   Science (PCS) Director  leads  therapy area and project-level patient- centered   evidence strategies , with a focus on  clinical outcome assessments (COAs) ,  patient-reported outcomes (PROs) , and broader  patient experience data  across the product lifecycle.    The role ensures that patient- centered   evidence is  fit for purpose  and supports  regulatory approval ,  HTA/reimbursement needs , and  commercialization .   The role holder partners with cross-functional teams to define the most   appropriate  COA/PRO   endpoints ,   identify   evidence gaps, and recommend or develop instruments and methods that capture the   patient   experience and meet stakeholder expectations. They provide strategic leadership from early development through late-stage programs, ensuring that patient- centered   evidence is integrated into  clinical plans ,  TPPs/ TPCs ,  regulatory discussions , and  submission   dossiers .   The PCS Director is accountable for leading  patient input activities , including interviews and related evidence-generation approaches, and for translating those insights into scientifically robust recommendations. The role also   represents   PCS in interactions with  regulatory authorities ,  HTA bodies , external experts, and internal governance teams, while supporting payer   evidence   needs such as  utility  and  patient preference measurement .   In addition, the PCS Director drives consistent TA-level standards for PRO/COA strategy, oversees relevant vendors and subprojects, contributes to scientific communications and publications, and strengthens AstraZeneca’s external reputation in  patient- centered   measurement science .   Key Responsibilities   Lead PCS strategy  for assigned therapy area(s) and projects, covering  COA ,  PRO , and  patient experience  evidence needs across development.   Advise teams on endpoint strategy , including   selection , development, validation, and implementation of fit-for-purpose instruments.   Identify   evidence gaps  and define plans to generate robust patient- centered   evidence for regulatory, payer, and clinical decision-making.   Provide input to clinical development plans ,  TPPs/ TPCs , protocols, briefing books, and regulatory submission packages.   Lead PCS regulatory and HTA interactions  related to PRO/COA evidence and support market access evidence needs where relevant.   Generate patient insight  through interviews and other research approaches to inform strategy and documentation.   Partner cross-functionally  with R&D, Medical, Payer, Regulatory, and external experts to align evidence plans and messaging.   Manage external vendors and subprojects , including scope, budget, timelines, quality, and deliverables.   Drive scientific communication , including presentations, publications, and external engagement to advance AZ’s leadership in PCS.   Minimum   Requirements   Bachelor’s degree  in   a clinical , biological, social science, or related field.   Master’s degree  in outcomes research, epidemiology, health services research, health policy, or   a related   discipline.   Doctoral degree MD preferred .   At least 5 years’ experience  in the biopharmaceutical industry.   Demonstrated experience in  COA/PRO  or broader  patient- centered   science .   Strong understanding of  clinical development ,  study design , and  evidence   interpretation .   Knowledge of  qualitative and quantitative methods  relevant to patient insight and outcome measurement.   Experience working across functions and with  external vendors/agencies .   Skills and Capabilities   Deep   expertise   in  PRO/COA strategy  and its application in pharmaceutical development.   Strong understanding of  global regulatory ,  HTA , and product development requirements.   Ability to translate patient- centered   evidence into  strategic recommendations  and actionable development plans.   Strong scientific leadership, problem-solving, and stakeholder management skills.   Excellent communication, collaboration, and influencing skills.   High integrity and strong ethical standards.   Key Interfaces   The role works closely with  R&D   project teams,  Regulatory ,  Payer and Evidence teams , external consultants, academic partners, and  regulatory/HTA authorities .   The annual base salary for this position ranges from $194,147.00 to $291,220.00. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca offers an environment where you can make a positive impact while building a long-term career filled with global opportunities. Our commitment to delivering accelerated growth pushes us to innovate continuously. With a focus on Lean processes, cutting-edge science, digitalization, and sustainable practices, we are dedicated to making people's lives better. Our inclusive community supports each other on our journeys, fostering curiosity and problem-solving. Embrace the chance to broaden your knowledge and skills in a place where your dedication is rewarded. Ready to take on this exciting challe