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Director, Theranostics and Radiation Science

AstraZeneca · Massachusetts

📍 US - Boston - MA💰 $203,709via workday
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At AstraZeneca, we’re building a different kind of biopharmaceutical company—one that redefines how transformational oncology medicines are conceived, developed, and delivered. Oncology Targeted Discovery accelerates impact by attacking cancer from multiple angles through innovative modalities, combinations, and precision regimens. The Director, Theranostics and Radiation Science will play a key role in supporting the management, mentorship, and development of the Radiation Sciences team. You will help guide and support team members,   fostering   collaboration and professional growth within the team.   In addition to leadership, you   will oversee key processes and work cross-functionally with divisions across   Imaging and   Radioconjugate   development , including but not limited to Clinical Operations, Preclinical Teams, Pharmacometrics, DMPK, and Regulatory Affairs. The role will also involve working with and helping manage external vendors and contractors to ensure the successful execution of ongoing and upcoming clinical trials.   This position requires a   scientific and   strategic mindset, stron g   technical background , and the ability to navigate complex projects while collaborating effectively across internal and external stakeholders.   Responsibilities   Optimize and review nuclear medicine imaging protocols, including quality control parameters, image acquisition and reconstruction, radiation dose determination, and protocol dose management.   Define requirements and technical support for imaging execution at clinical sites, ensuring proper implementation and adherence to study protocols.   Design and oversee quality control protocols, working with both internal teams and external partners for imaging review and processing.   Provide training, mentorship, and problem-solving support to internal and external clinical study teams to ensure study   objectives   are met.   Perform image-based, patient-specific dosimetry calculations (internal dosimetry, not external beam radiation therapy [EBRT]).   Collaborate with the Radiation Sciences team on imaging protocol optimization, ensuring alignment with best practices in QC, image acquisition, radiation dose management, and compliance with regulatory standards.   Support regulatory compliance efforts related to radioactive materials, staying current with guidelines from regulatory and professional organizations (e.g., SNMMI, NRC, and international regulatory bodies).   Contribute to research and discovery projects as needed, providing scientific and technical   expertise   to advance innovation in radiation sciences and molecular imaging.   Basic Qualifications   BS degree in physical sciences ,   mathematics   or other physical   sciences   followed by a graduate degree (M.S. or PhD) in medical physics,   physics   or related scientific disciplines.   Medical physics residency or Post   Doctoral training   with   5 +   years of   Industry and/or   clinical experience (post residency) .   Knowledge and Experience with personalized dosimetry for radiopharmaceuticals, experience with programs such as Olinda, MIM and other imaging   and dosimetry   packages   is   required .   Preferred Qualifications Board certification   is   preferred but not   required .    Prior industry experience is preferred but not   required .   Experience with radiopharmaceuticals, Nuclear Medicine,   SPECT   and PET imaging techniques,   reconstruction,   and camera quality control procedures   are preferred.   Strong   concepts in radiation biology and radiation physics are preferred.   Advanced technical computer skills and thorough understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS   is   required   and , client/server architectures   and   image processing   is preferred.   Understanding of imaging-related project needs as expressed in a clinical study   protocol.   Experience with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g.   AAPM ,   SNMMI, NRC, and other country regulatory bodies)   The annual base salary for this position ranges from $203,709-.305,564 However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.  When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.  Date Posted 07-May-2026 Closing Date Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider

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