Executive Medical Director, Global Medical (Nephrology)

Job Description General Summary: The Executive Medical Director, Global Medical Lead (GML), Nephrology is a critical leadership role in Global Medical, responsible for the global medical strategy and implementation and tracking of global activities for a designated disease area(s). Key accountabilities include, but are not limited to, disease area specific Integrated Medical Plan development, including the publication plan, integrated evidence generation plan, global medical launch strategy and execution, scientific leadership, external medical expert engagement, and strategic alignment with commercial and other cross-functional business partners.. This leader reports directly to the VP, Global Medical and is a core member of the Global Medical leadership team. They will lead the global medical affairs team for the designated disease area(s) and represents Medical Affairs in all Global strategic teams with Development and Commercial, including the Disease Strategy Team (DST) to drive cross-functional alignment, anticipate future needs, and contribute to Medical Affairs and Vertex’s long-term success.  Key Duties and Responsibilities: Medical Strategy   Lead the development, implementation, execution, and communication of the Integrated Medical Plans, including but not limited to medical strategy, global tactical plan, publication, congress and evidence generation plans, in collaboration with Clinical Development, Clinical Operations, HEOR, RWE, Medical Writing, and other internal stakeholders across Vertex   Ensure alignment of medical strategy with organizational objectives by integrating individual and disease area team goals with Vertex and DST priorities, and the goals of cross-functional partners  Expertly distills insights and actionable outcomes that inform strategy and drive the greatest impact for Medical Affairs   Establishes and tracks medical KPIs that demonstrate impact on asset strategy and patient outcomes.  Applies structured problem-solving and root cause analysis to identify solutions and make decisions that maximize medical and asset strategy  impact  Able to identify what is important and impactful to medical and the wider organization, prioritize competing demands and communication to key stakeholders  Accountable for development of the global DA budget, management of funds allocation, and associated tracking to ensure alignment with Medical Affairs priorities and efficient resource allocation  Scientific Excellence   Serve as product and disease area expert and Global Medical primary contact point for all global disease area related issues with the external community and internally at Vertex  Able to lead development of peer reviewed publications, congress presentations and evidence generation to inform clinical practice  Lead the development of global scientific communications and materials including materials for global led symposia, advisory boards, and training.  Accountable for medical review of assigned brand related content and global medical content aligned with Vertex SOPs  External Partnerships   Represent Vertex at scientific and medical forums, including medical education forums, scientific societies, patient advocacy groups, and congresses.  Accountable for engaging and cultivating professional relationships with leading global key thought leaders (TL) to gain greater understanding of the disease area, and insights into unmet patient needs  Medical Communication   Tailors communication to stakeholder needs, building trust and understanding across diverse audiences.  Deliver external presentations (advisory board meetings, symposia, other medical education meetings) to enhance the medical knowledge of pipeline and marketed products, as required and in accordance with relevant regulations and procedures  Support disease area training across the company as required  Responsible for medical interpretation of data (clinical trials, registries, published literature, etc.) for pipeline therapies and marketed medicines  Regional Medical and Cross Functional Collaboration   Accountable for the medical component of the go to market model In absence of regions teams, medical components of the country go to market model remains the responsibility of the GML.  Support regional Medical Affairs and Medical Excellence teams from launch through lifecycle via timely delivery of fit-for-purpose training and core materials.  Responsible for driving alignment on medical content/messaging within the organization to ensure maximal functional and regional input.  Medical Affairs leader on key global cross-functional product and development strategic focused teams, including DST and relevant sub teams  Effectively represents and communicates DST priorities to the medical function and proactively communicates and represents medical needs to DST  Chair the Global Medical Area Team (GMAT) for the disease area and accountable for deliverables  Provide strategic Medical Affairs leadership on relevant commercial teams: Launch Team, and Global brand teams for product  Represent Medical Affairs in label discussions  Support Access, Patient Advocacy, Policy, and Corporate Communications teams with medical/scientific expertise and materials review.  Evidence Generation and Access   Accountable for the  strategy, development and execution of Life Cycle Management studies  in partnership with HEOR, including Integrated Evidence Generation plan in close collaboration with key internal stakeholders   May act as medical monitor for studies falling under the Medical Affairs scope in collaboration with Clinical Development, Real World Evidence, Health Economics and Outcomes Research, and Clinical Operations  Lead oversight and management of ISS programs, and in collaboration with Regional Medical leadership, conduct critical scientific and medical review of ISS protocols   As applicable, lead Managed Access Committee for assets with a Managed Acc