Financial Planning & Analysis Manager

Job Description Vertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation to create transformative medicines for people with serious diseases. The finance organization is integral to achieving our company’s strategic goals, providing critical insights and analysis in support of decision-making across the organization.   By joining Vertex’s Finance organization, you will become part of a fast-moving, forward-thinking team to support the ongoing growth of a leader in the biotechnology industry. The Finance Manager, Regulatory and Quality is a key member of Vertex's Financial Planning & Analysis organization, serving as a trusted business partner to leaders across the Research and Development (R&D) functions. This role partners closely with stakeholders across the Regulatory and Quality functions, providing financial direction and strategic insights to enable delivery against short-term and long-term goals. As a strategic business partner, you will identify key value drivers and business KPIs, ensuring that all functional activities are appropriately reflected in company budgets, forecasts and leverage analytics – including emerging tools in automation and AI – to enhance decision-making and operational efficiency This position is based in our Boston, MA location (Seaport area) and requires a hybrid work schedule with 3 days in office /2 days remote on a weekly basis. Key Duties & Responsibilities:   Business Partnering & Stakeholder Management Serve as a strategic business partner to Regulatory and Quality leadership, building trusted relationships and providing financial counsel that influences business strategy and operational decisions Partner proactively with cross-functional stakeholders to understand business priorities, anticipate needs, and deliver actionable financial insights that drive performance Collaborate with Human Resources on headcount reporting, forecasting, and planning to support organizational growth and talent strategy Work closely with other members of the CFO organization, including Clinical Finance, Manufacturing Finance, Corporate Finance, Strategic Sourcing, and Accounting—to maintain a continuous improvement mindset and promote strong communication, sharing of best practices, and efficient processes Financial Planning & Analysis Lead the financial planning process (annual budget, forecasts, long range plan, etc.) for Regulatory and Quality organizations to provide relevant, forward-looking observations, and develop key scenarios to support strategic decision-making Conduct financial performance management across the Regulatory and Quality functions with a focus on influencing business operations through a deep understanding of   key performance drivers, risks, and opportunities Build, manage and continuously improve analytics and transparent reporting to drive forecast accuracy, inform on key drivers of any variances to plan, and provide full transparency on risks and opportunities for both operating and capital expenses Reporting & Compliance Perform the monthly/quarterly accounting close for expenses and accruals, including flux analysis and compliance with SOX control requirements Develop and maintain the functional teams’ monthly financial reporting and analysis packages; and assist in the consolidated monthly and quarterly financial review presentations Innovation & Future Skills Identify and implement opportunities to leverage automation, AI and advanced analytics and visualization tools to enhance forecast accuracy, streamline reporting processes, and deliver deeper business insight Stay current on emerging finance technologies and methodologies; champion the adoption of innovative solutions to drive efficiency and effectiveness within the finance function Education and Experience: Bachelor’s Degree in Finance, Economics, or related quantitative/analytical field 6+ years of progressive experience in finance roles (FP&A, business partnering, or related areas) demonstrating strong technical and analytical skills and a proven track record of success working in a team-based environment or the equivalent combination of education and experience Biotechnology/Pharmaceutical industry experience preferred Knowledge and Skills: Core Financial & Analytical Expertise Exceptional analytical and financial modeling skills to evaluate a broad range of financial questions and complex business decisions Advanced proficiency with Excel and strong PowerPoint skills Experience with Hyperion or similar multidimensional databases (e.g., Oracle EPM, SAP BPC); familiarity with business intelligence and data visualization tools (e.g., Tableau, Power BI) strongly preferred Understanding of Accounting and Finance principles Business Partnering & Communication Outstanding stakeholder management skills with a demonstrated ability to build strong, trusted relationships across all organizational levels—from senior executives to functional partners Excellent communication skills (written and verbal) with the ability to translate complex financial data into clear, actionable insights for non-finance audiences Proven ability to influence business decisions and drive alignment through financial storytelling and strategic counsel Leadership & Change Management Ability to lead and drive change in a dynamic business environment, coordinating processes involving multiple stakeholders, complex systems, and tight deadlines Strong business acumen, sound judgment, and knowledge of industry trends, market dynamics, and competitive landscape High degree of ownership and accountability for work product, with the flexibility and agility to adapt to changing priorities Innovation & Technology Interest in developing skills in AI, automation, and emerging finance techn