Senior Clinical Scientist

About Jade Biosciences   Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit  JadeBiosciences.com  and follow the Company on  LinkedIn .   Role Overview   We are  seeking   a highly motivated and experienced  Senior Clinical Scientist  to  support  clinical  development  programs in nephrology ,  with a focus on rare or immune-mediated kidney diseases .  This individual will play a key role in translating clinical strategy into high-quality execution of  late-stage phase  clinical trials .  This is an exciting opportunity to join a growing biotechnology company where individual contributions have  significant  impact. The ideal candidate thrives in a fast-paced, collaborative environment,  demonstrates  strong scientific and operational  expertise , and takes ownership of key deliverables.   This newly created position will report to  the Executive Medical Director of Clinical Development .  The role is fully remote and will require periodic travel for investigator meetings, study team meetings, conferences, and other business activities.   Key Responsibilities   Clinical Development and Study Execution   Serve as the Clinical Scientist for one or more Phase 2 and/or Phase 3 clinical studies.    Contribute to study design, protocol development, and protocol amendments.    Develop and review study-related documents including:    Protocols   Investigator's Brochures   Informed Consent Forms   Clinical study reports   Study manuals and training materials   Safety management plans   Provide scientific oversight throughout study conduct to ensure protocol compliance and data quality.   Partner closely with Clinical Operations to support study start-up, enrollment, trial execution, and close-out activities.    Participate in investigator meetings, site training, and scientific discussions with investigators and key opinion leaders.   Data Review and Interpretation   Lead ongoing data review and medical monitoring activities in collaboration with Medical Monitors.   Identify clinical trends, protocol deviations, safety signals, and data quality issues.   Collaborate with Data Management and Biostatistics to develop:    Data review plans   Edit check specifications   Endpoint derivation and analysis plans   Participate in database lock, data cleaning, and analysis activities.   Contribute to interpretation of study results and development of key messages.   Regulatory and Documentation Support   Support preparation of regulatory submissions and agency interactions.   Assist in development of briefing documents and responses to regulatory questions.   Ensure study conduct aligns with ICH-GCP, applicable regulations, and company standards.   Cross-Functional Collaboration   Work effectively across Clinical Development, Clinical Operations, Biometrics, Regulatory, Safety, Medical Affairs, and Medical Writing.   Drive timelines, track deliverables, and proactively identify and mitigate risks.   Support governance meetings and preparation of study review materials.   Scientific Communication   Contribute to abstracts, presentations, manuscripts, and scientific publications.   Participate in advisory boards, investigator meetings, and key external scientific interactions.   Maintain awareness of evolving scientific, clinical, and competitive landscapes.   Qualifications   Required   Advanced degree in life sciences, nursing, pharmacy, public health, or related discipline (PharmD, PhD, MS, MPH, or equivalent).   Minimum 5–8 years of clinical research experience in the biotechnology, pharmaceutical, or CRO industry.   Experience supporting Phase 2 and/or Phase 3 clinical trials.   Strong understanding of clinical trial design, clinical data review, and drug development.   Working knowledge of ICH-GCP, FDA, EMA, and global regulatory requirements.   Experience reviewing clinical data and collaborating with biostatistics and data management teams.   Excellent project management, communication, and organizational skills.   Ability to work independently and manage multiple priorities in a fast-paced environment.   Preferred   Experience in nephrology, immunology, inflammation, autoimmune diseases, or rare diseases.   Experience with global multicenter clinical trials.   Prior involvement in regulatory submissions and health authority interactions.   Experience contributing to scientific publications and conference presentations.   Experience working in a small or emerging biotechnology company.   Skills and Competencies   Strong scientific and analytical thinking   Attention to detail with a focus on data quality   Excellent written and verbal communication skills   Collaborative and team-oriented mindset   Ability to influence across functions without direct authority   Comfortably operating in a highly dynamic, entrepreneurial environment   Proactive, hands-on, and solution-oriented approach   Position Location   This is a remote role; periodic travel to team and company events is required.   The anticipated salary range for candidates for this role is $175,000 - $190,000 . The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational backg