Senior Director, Global Digital & Technology Systems Engineering

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. BeOne is a global biopharmaceutical company dedicated to the discovery and development of innovative drug therapies for the treatment of cancer. At BeOne we believe that access to life-changing medicine sees no borders. General Description: The Senior Director, Global Digital & Technology Systems Engineering operates primarily as the primary point of contact and strategic bridge to the Global Technology Solutions (Enterprise IT function), ensuring all business-specific systems align with Enterprise infrastructure, security, identity management, and cloud platform standards. The role owns the end-to-end remit for systems engineering for externally developed platforms & solutions, integration engineering, and technical application lifecycles across the organization. This includes designing, configuring, and deploying high-performance computing (HPC) clusters and containerized environments, alongside implementing modern system observability frameworks and robust data pipeline integration architectures. Additionally, this leader acts as a deep technical subject matter expert who advises on and engineers foundational AI architecture and systems engineering patterns, including advanced RAG pipelines, agentic AI frameworks & multi-modal integration patterns.   As a member of the GRDTS Leadership Team, the Senior Director is an active contributor to developing and executing BeOne’s R&D systems engineering strategy, defining necessary technology investments, and driving transparency in prioritization and planning. The Senior Director and their team are responsible for ensuring the strategy is fully aligned with business needs, positioning GRDTS to deliver and realize compelling business value. A successful candidate is a dynamic leader who brings deep end-to-end pharma / biotech domain knowledge with technical expertise related to digital & technology systems, systems engineering, processes, data science, analytics, AI, & genAI. Ability to manage multiple projects across different sub-functions in a global, geographically diverse environment, and building and sustaining teams in times of ambiguity are all critical success factors for this role. An ideal candidate will adapt communication cadences and problem-solving skills to accommodate stakeholders, partners, and team members, exercise diplomacy and effective influence to reach consensus, and build strong relationships. Essential Functions of the job: Enterprise IT Alignment & Collaboration Serve as the single point of contact and strategic bridge to Global Technology Solutions (Enterprise IT function), ensuring R&D systems align with global infrastructure, corporate cybersecurity, identity management, and cloud platform standards while advocating for specialized technical requirements. Platforms & Systems Engineering Oversee the engineering, architecting, and deployment strategies for platforms & systems, balancing on-prem, hybrid cloud, and multi-tenant SaaS environments based on business needs. Architect robust, low-latency API layers and data buses to bridge disparate third-party applications, ensuring seamless data interoperability across the end-to-end organizational pipeline. Implement modern observability frameworks, distributed tracing, and real-time telemetry across infrastructure and applications to proactively manage system health, identify bottlenecks, and resolve failures. Lead the design, configuration, and deployment of High-Performance Computing (HPC) clusters and containerized environments optimized for compute-heavy, complex processing systems. Provide oversight for the engineering and maintenance of the underlying storage fabric, data lakes, and pipelines that manage the full ingest, storage, and processing lifecycle of datasets for the Research function. Manage the systems engineering and product development lifecycle, codebase evolution, patch management, and automated deployments of customized platforms and applications, ensuring long-term technical sustainability for the Research function. Foundational AI Architectures & Workflow Patterns Act as the technical SME & oversee the design, on Retrieval-Augmented Generation (RAG) architecture, engineering vector storage integrations, advanced chunking strategies, and semantic retrieval layers. Design and implement agentic AI system patterns, orchestrating multi-agent frameworks that can securely handle complex, multi-step autonomous workflows and tasks. Engineer pipelines capable of handling multi-modal AI inputs and outputs, allowing core systems to ingest, process, and reason across diverse data types simultaneously. Change Management & Digital Adoption Manage the technical change strategy for foundational infrastructure overhauls and cloud migrations in collaboration with GTS. Drive organizational alignment around unified integration standards, guiding systems engineering, development, and vendor teams toward optimized technical architectures. Governance & Risk Mitigation Collaborate with Global Technology Solutions (Enterprise IT) in the technical implementation of secure, enterprise-grade AI proxy layers and gateways, ensuring that proprietary data, information & systems,  and intellectual property are strictly sandboxed. GRDTS Leadership: Team Leadership & Talent Development: Lead, mentor, and manage a high-performing GRDTS team focused on Systems Engineering. Foster a culture of innovation, accountability and drive professional development. Operational Excellence, Compliance & Governance: Ensure all systems and platforms adhere to relevant pharmaceutical industry regulations and internal security policies